
New Patients
Old Patients
Details of PNI Evaluations
Brief Bio of Dr. Neppe
Psychiatric Diagnosis
Head Injury
Cry The Beloved Mind
Déjà Vu
About Dr. Neppe
PNI More Information
Instruments
Research
Forensics
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PNI'S
ADDRESS | WHAT
PNI DOES | PATIENT PROFILE
| REFERAL SOURCE | APPROACH
| TESTS ON NEW PATIENTS
| DR NEPPE'S BACKGROUND
PNI's
Address
Pacific Neuropsychiatric Institute
Seattle Healing Arts Center
6300 Ninth Ave NE, Suite 353,
Seattle, WA 98115
Tel: 206.527.6289 (or "lap navy")
URL: http://www.pni.org/
Email: clinical@pni.org
What the Pacific Neuropsychiatric Institute
Does
The focus of the Pacific Neuropsychiatric Institute
is mostly face to face clinical consultations for patients
with neuropsychiatric and psychopharmacologic difficulties.
This includes disease processes with behavioral or
psychological difficulties associated with known
or suspected neurological conditions such as
epilepsy, head injury, attention deficit disorder, dementia,
tardive dyskinesia, atypical spells, irritability and
any organic mental disorder. We also evaluate difficult
to treat psychological or psychiatric conditions,
including problems relating to medication. Unfortunately,
the PNI cannot do any specific consultations over the
world wide web and any EMails or other communications
in that regard will necessarily not be answered.
The evaluation goal is to provide a blueprint not
only for the present but directions for the patient's
primary physician (generally necessary) to manage the
patient in the future.
Generally, Vernon M Neppe MD, PhD, is the Director
of the Pacific Neuropsychiatric Institute (PNI), comprehensively
evaluates all new patient referrals necessarily over
several consultations. (Generally 4 to 5 plus
extensive testing).
Patient Profile
Outpatients with both complex and simple problems
who require or request detailed assessment for behavioral
or psychological, emotional or thinking difficulties
associated with known or suspected neurological
or medical conditions who are referred by physicians
and have a primary care follow-up physician may be suitable
provided they pass the appropriate screens.
The kinds of patient spectrum reflect behavioral
or psychological, emotional or thinking difficulties
associated with known or suspected neurological
or medical conditions Diagnoses include epilepsy,
head injury, attention deficit disorder, dementia, tardive
dyskinesia, subjective paranormal / psychic experience,
blackouts, unusual episodes or atypical spells, irritability
or aggression, Parkinson's disease, narcolepsy and sleep
problems, pain or headache, obesity, endocrine disorder
and any organic mental disorder. The PNI sometimes
evaluates difficult to treat psychiatric conditions,
such as non-responsive psychosis, depression
and panic, including problems relating to medication.

Referral Source
Patients are generally referred from other physicians
or other health care professionals for a neuropsychiatric
and/or psychopharmacologic evaluation. They are then
referred back to their original referring physicians
when appropriate. Referrals to follow-up physicians
may occur after weeks or months depending on circumstances.
For example, the referring doctor may wish to separate
pharmacologic from psychotherapy management, or just
be requesting a second opinion, or may want a guide
to the pharmacologic or neuropsychiatric elements, or
sometimes the patient prefers not to consult with their
previous physician. Optimally, we want to work with
the referring doctor or therapist.

Approach
The major approach is towards pharmacologic management
of the pathophysiologic difficulties (not psychotherapy)
although the PNI tries to be very aware of the relevance
of the biopsychofamiliosociocultural perspective. Patients
generally complete detailed questionnaires on computers
or paper, plus tests given face to face and other tests
like EEGs, ambulatory EEGs, MRIs or blood tests as deemed
necessary with their assessment. The tests generally
take two or three half day sessions. They may involve
psychosocial screening, personality, behavioral and
psychodiagnostic evaluations, special evaluations of
areas of the brain such as the temporal lobe or for
specific neuropsychiatric abilities and deficits. The
evaluation goal is to provide a blueprint not only for
the present but directions for the patient¹s primary
physician (generally necessary) to manage the patient
in the future. Referrals to follow-up physicians may
occur after weeks or longer depending on circumstances.

Tests
on New Patients
Please note that all new patients are evaluated in
detail by both clinical consultation and neuropsychiatric
testing. When certain tests have been done recently
elsewhere, they usually do not need to be repeated.
The clinical consultations of new referrals
generally require several (usually three, four or five)
complex / comprehensive consultations / evaluations
which include physical and neurologic examination. A
very extensive report is frequently prepared at the
completion of the evaluation.
Dr Neppe's Background
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Vernon M. Neppe: MD, PhD(Med), FRSSAf, FAPA, FFPsych(SA), FCPsych, FRCPC, MMed (Psych), DABFM, DABFE, FACFE, MB, BCh, DPM, BA, is Director and President of the Pacific Neuropsychiatric Institute (PNI) in Seattle and practices medicine in Washington state. He is also (Adjunct Full) Professor of Psychiatry and Human Behavior, St. Louis University School of Medicine, St. Louis, MO and formerly Director, Division of Neuropsychiatry, University of Washington, Seattle, WA
Prof. Neppe is an internationally recognized psychopharmacologist, neuropsychiatrist and behavioral neurologist, psychiatrist, geriatric psychiatrist, epileptologist and forensic specialist. He is also an accomplished author and playwright. His books on brain medications include Cry the Beloved Mind: A Voyage of Hope and Innovative Psychopharmacotherapy and amongst his other books are The Psychology of Déjà Vu and three books from early 2006 How Attorneys Can Best Utilize Their Medical Expert Consultant: A Medical Expert’s Perspective; Déjà Vu Revisited; and Déjà Vu: A Second Look (as well Déjà Vu Glossary and Library) and his most important play is Quakes.
Dr Neppe has numerous American Board Certifications as well as non-American specialist qualifications. He is Board Certified by the ABPN in psychiatry and has had further sub-certifications in geriatric psychiatry (91-01-11) and forensic psychiatry (94-04) . He is also boarded by the ABFE as a Forensic Examiner and in Forensic Medicine. He also has overseas specialist qualifications with majors in Psychiatry and Neurology.
In 1986, Professor Neppe established (and became Director of) the first Division of Neuropsychiatry in a Department of Psychiatry in the United States (at the University of Washington) His major current academic university affiliation is as (adjunct full) Professor of Psychiatry and Human Behavior at St Louis University, St Louis, MO. He is also an attending physician at Northwest Hospital, Seattle and Overlake Hospital.
Dr Vernon Neppe founded the PNI in Seattle, WA in late 1992. Prior to that, he had trained and worked at the University of Witwatersrand, Johannesburg, South Africa (medical degree, internship, specialist post-graduate training and as a consultant attending then senior consultant). He was also honored as the Witwatersrand University Overseas Traveling Fellow for 1982-3 and worked at Cornell University Medical College, New York where he consolidated his psychopharmacology, chronobiology and sleep-wake disorders, epileptology, geriatric and neuropsychological experience. Dr Neppe was formerly Director of the first Division of Neuropsychiatry in a Department of Psychiatry in the United States: This was at the University of Washington--- he was recruited there from South Africa after an international search
He is a fellow of seven and member of twelve professional associations (including the American or International Psychiatric, Medical, Neuropsychiatric, Epilepsy, Psychogeriatric and Clinical Psychopharmacology Associations and Societies) and his Consultancies have included the Epilepsy Institute and the American Psychiatric Assn Diagnostic and Statistical Manual.
Dr Neppe is listed in the peer-reviewed Americas Top Doctors (all five editions)—most recently listed under the disciplines of Forensic Neuropsychiatry, Neuropsychiatry/ Behavioral Neurology and Psychopharmacology. Prior to that, he was again via peer review listed in The Best Doctors in America (apparently all editions of this discontinued Woodward White book). He is also listed in the current Marquis Who'sWho in the World (first listed 1993-4). Amongst his numerous other special honors has been book listings in, Men of Achievement, Five Thousand Personalities of the World, Two Thousand Notable American Men, Five Hundred Leaders of Influence, Great Minds of the 21 st Century and Americas Top Psychiatrists. Dr Neppe was an International Man of the Year 1992-3 from the International Biographical Center in Cambridge, England "in recognition of his services to Neuropsychiatry, Psychopharmacology and Anomalistic Psychology." He was one of 3 winners worldwide of the Rupert Sheldrake New Scientist Research Hypothesis Competition (1983, London) and received the Marius Valkhoff Medal in 1982. In 2002, he was honored for his scientific contributions as apparently the first USA based physician to be elected a Fellow of the Royal Society of South Africa. In 2004, he was elected a Fellow of the American Psychiatric Association.
Professor Neppe has extensive scientific publications (more than 300 listed in his CV) in all six habitable continents. He has lectured in a dozen countries and at about 90% of the medical schools in the USA. He has chaired international conference symposia, and has had radio and television appearances round the world. He is founding editor of a journal, has been guest editor of another and on the editorial boards of numerous others and has authored numerous chapters in key text books. His play Quakes became public with a staged play reading in Hawaii in 2004. He has also proposed a major philosophical theory, Vortex Pluralism.
Dr Neppe has recently been chosen to be the sole leader of the United States (plus international delegation) in Psychopharmacology and Neuropsychiatry to China in June 2006 through the Ambassador People-to-People Program initially established by President Eisenhower.
Professor Neppe's major research areas include pharmacologic, neuropsychiatric and phenomenologic elements. He developed several measuring neuropsychiatric instruments and inventories including the BROCAS SCAN (Screening Cerebral Assessment of Neppe), The INSET (Inventory of Neppe of Symptoms of Epilepsy and the Temporal Lobe), the STRAW (the first time / severity measure for tardive dyskinesia), a geriatric inpatient instrument namely the PBRS (with JP Loebel) (The Problem Behaviors Rating Scale) as well as research Subjective Paranormal Questionnaires and Narcolepsy Questionnaires. Additionally, he first demonstrated the links of anomalistic psychological experiences (subjective paranormal experience) with the temporal lobe of the brain. His pharmacologic areas include the only double blind study demonstrating the value of carbamazepine in dyscontrol and psychosis thereby being a major pioneer of the whole area of anticonvulsant drugs in psychiatry and benefiting millions of patients, the use of high dose buspirone as a successful treatment for tardive dyskinesia, and the extended use of azapirones in aggression and attention deficit disorder. He has also developed concepts in medical areas such as deinduction, non-vertiginous dizziness, dysproccia, chindling and possible temporal lobe symptoms. He has also developed concepts in pharmacological areas such as deinduction, non-vertiginous dizziness, and chindling.

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