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Foreword to Innovative Psychopharmacotherapy

This is an important and useful book. One of the major facets of university hospitals is that they most often end up caring for treatment failures. "Our practices are atypical in that most of the patients are either diagnostic prob-lems or refractory to the usual treatments. Consequently, physicians work-ing in university settings have built up vast clinical experience with diag-nostic and treatment puzzles." This is probably the converse of the experience of most practitioners, where the majority of their patients re-spond quite nicely to the standard treatment regimens. in this volume, Dr. Neppe and his colleagues have put together their vast clinical experience with difficult treatment situations. This is a book that experienced clinicians will turn to when patients do not respond to the usual forms of treatment. It is a work that attempts to chart a course in an uncharted land where there are very few scientific studies. Numerous studies are quoted, but much of the book is based on the clinical impressions of experienced clinicians. However, the import and uniqueness of this book rests on the fact that the authors attempt to provide a theoretical framework with which to approach patients who have not responded adequately to treatment. Much of this theoretical framework is based on information from the most current biologic data about the functioning of the central nervous system. As such, while speculative, this volume should provide the basis for many future studies. I know clinicians will find that they frequently refer to this book, not only for its utility but also for its review of the literature, which will save many hours of library work. it is a most useful compendium and framework for experienced clinicians and should provoke much discussion and thought in the field.

Gary J. Tucker, M.D.
Chairman
Department of Psychiatry and Behavioral Sciences
University of Washington
Seattle, Washington
1989

 

 


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