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Overview: Beta-Adrenergic Blocking Agents: Perspectives in Psychiatry

From Innovative Psychopharmacotherapy

Vernon M. Neppe

The beta-adrenergic blocking agents have been used for a wide variety of medical and psychiatric indications. Amongst those psychiatric indications that involve current serious usage are anxiety, rage, psychosis, and stress. The application of beta-adrenergic blocking agents to these four conditions is discussed in detail. The special perspective of appropriate use of these drugs, namely, monitoring of psychophysiological parameters as a means of adequately titrating dosage and careful choice of drug depending on degree of lipid solubility are particularly discussed as are the actions at neurotransmitter levels in the brain. The choice of beta-adrenergic blocking agent between such drugs as propranolol with its extensive research base and the largely non-lipid soluble agents such as nadalol with their limited psychiatric research base is discussed in some detail.

Keywords

Beta blockade, Beta blockers, Beta-adrenergic blocking agents, Dosage, Indications Anxiety, Lipophilicity, Properties Psychosis, Pulse, Rage, Stress, Tremor, Use, Withdrawal

 

 


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